Somatodendritic Currents and Spike Direction
 
 

CA1 single neuron model

     
      Several projections of the model neuron:
       
    2D projection of the 3D morfology 2D orthogonal projection of the 3D morphology
2D projection on the x plane 2D projection on the X plane
2D projection in the y plane 2D projection on the Y plane
2D projection in the z plane 2D projection on the Z plane
     
    The prototype model neuron was built with an average dendritic branching pattern, and total dendritic length obtained from detailed morphometric studies (Bannister and Larkman, 1995 a,b; Trommald et al., 1995). The 3D morphology of the neuron was simulated using 265 compartments, distributed in an axon, (consisting of mielinized portions, Ranvier nodes, initial segment and axon hillock), soma and apical and basal dendritic trees (2D projections of the model neuron are shown in the figures above). Total effective area of the neuron was 66,800 microns2 (including spine area).
The electrotonic parameters of the model were Rm=70,000 ohms×cm2, Ri=75 ohm×cm and Cm= 0.75 µF/cm2. Values of Rm and Cm at the dendritic compartments were compensated to take into account spine area. Input resistance at the soma was 140 Mohms, and tau was 25 ms. See neuron scripts for the exact values of the electrotonic parameters used for the neuron prototype.


Back to main menu